Angelo Antonini

The Parkinson's Disease and Movement Disorders Unit operates at the Neurological Clinic of the University Hospital of Padua and consists of a large and multidisciplinary team of neurologists, psychologists, bioengineers, clinical and laboratory researchers. The focus is on translational research, whereby new discoveries in the laboratory are brought to the clinical program to offer new treatments to patients and, just as importantly, the findings resulting from the clinic are studied in the laboratory to understand the underlying scientific mechanisms.

The group's mission includes three parts of excellence:

1) patient care that is multidimensional and applicable to all phases and aspects of movement disorders in both adult and pediatric age;
2) research with cutting-edge scientific studies;
3) interaction with patient associations, families and health professionals to improve their education.

Our clinical and research programs include:

- Parkinson's disease;
- Multiple System Atrophy;
- Progressive Supranuclear Palsy;
- Huntington's disease;
- Adult and pediatric dystonia;
- Gilles de la Tourette's syndrome and tic disorders;
- Disorders related to fragile X.

Palermo G, Frosini D, Antonini A, Ceravolo R. Early Compensatory Mechanisms in LRRK2 Mutation Carriers. Mov Disord. 2022 Mar;37(3):662-663. doi: 10.1002/mds.28908. Epub 2022 Jan 10. PMID: 35005801.

Antonini A, Odin P, Schmidt P, et al. Validation and clinical value of the MANAGE-PD tool: A clinician-reported tool to identify Parkinson's disease patients inadequately controlled on oral medications. Parkinsonism Relat Disord. 2021;92:59-66. doi:10.1016/j.parkreldis.2021.10.009

Kaasinen V, Vahlberg T, Stoessl AJ, Strafella AP, Antonini A. Dopamine Receptors in Parkinson's Disease: A Meta-Analysis of Imaging Studies. Mov Disord. 2021 Aug;36(8):1781-1791. doi: 10.1002/mds.28632.

Biundo R., Weis L., Fiorenzato E., Pistonesi F., Cagnin A., Bertoldo A., Anglani M., Cecchin D., Antonini  A. The contribution of beta-amyloid to dementia in Lewy body diseases: a 1-year follow-up study. Brain communications, 2021 3(3), fcab180. https://doi.org/10.1093/braincomms/fcab180

Bega D., Kuo P. H., Chalkidou A., Grzeda M. T., Macmillan T., Brand C., Sheikh Z. H., Antonini A. (2021). Clinical utility of DaTscan in patients with suspected Parkinsonian syndrome: a systematic review and meta-analysis. NPJ Parkinson's disease, 7(1), 43. https://doi.org/10.1038/s41531-021-00185-8

Sulzer D, Antonini A, Leta V, et al. COVID-19 and possible links with Parkinson's disease and parkinsonism: from bench to bedside. NPJ Parkinsons Dis. 2020;6:18. Published 2020 Aug 20. doi:10.1038/s41531-020-00123-0

Antonini A, Bravi D, Sandre M, Bubacco L. Immunization therapies for Parkinson's disease: state of the art and considerations for future clinical trials. Expert Opin Investig Drugs. 2020;29(7):685-695. doi:10.1080/13543784.2020.1771693

Emmi A, Antonini A, Macchi V, Porzionato A, De Caro R. Anatomy and Connectivity of the Subthalamic Nucleus in Humans and Non-human Primates. Front Neuroanat. 2020;14:13. Published 2020 Apr 22. doi:10.3389/fnana.2020.00013

Fiorenzato E, Strafella AP, Kim J, Schifano R, Weis L, Antonini A, Biundo R. Dynamic functional connectivity changes associated with dementia in Parkinson's disease. Brain. 2019 Sep 1;142(9):2860-2872. doi: 10.1093/brain/awz192..

Chaudhuri KR, Jenner P, Antonini A. Should there be less emphasis on levodopa-induced dyskinesia in Parkinson's disease? Mov Disord. 2019 Jun;34(6):816-819. doi: 10.1002/mds.27691.